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  1. 学術雑誌掲載論文
  2. 医学研究科

Structural and Functional Analyses of Retinal Ischemia in Eyes with Retinal Vein Occlusion: Relationship with Macular Edema or Microaneurysm Formation

https://ncu.repo.nii.ac.jp/records/2999
https://ncu.repo.nii.ac.jp/records/2999
766bf602-0759-483e-8c21-c111f3ffb32e
名前 / ファイル ライセンス アクション
J11-OR-00303747-61-218-hir.pdf J11-OR-00303747-61-218-hir.pdf (1.3 MB)
アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2021-11-30
タイトル
タイトル Structural and Functional Analyses of Retinal Ischemia in Eyes with Retinal Vein Occlusion: Relationship with Macular Edema or Microaneurysm Formation
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Optical coherence tomography angiography
キーワード
言語 en
主題Scheme Other
主題 Retinal thickness
キーワード
言語 en
主題Scheme Other
主題 Microperimetry
キーワード
言語 en
主題Scheme Other
主題 Retinal vein occlusion
キーワード
言語 en
主題Scheme Other
主題 Macular edema
キーワード
言語 en
主題Scheme Other
主題 Microaneurysm
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Tomiyasu, Taneto

× Tomiyasu, Taneto

en Tomiyasu, Taneto

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Hirano, Yoshio

× Hirano, Yoshio

en Hirano, Yoshio

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Suzuki, Norihiro

× Suzuki, Norihiro

en Suzuki, Norihiro

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Esaki, Yuya

× Esaki, Yuya

en Esaki, Yuya

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Yasuda, Yusuke

× Yasuda, Yusuke

en Yasuda, Yusuke

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Uemura, Akiyoshi

× Uemura, Akiyoshi

en Uemura, Akiyoshi

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Yasukawa, Tsutomu

× Yasukawa, Tsutomu

en Yasukawa, Tsutomu

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Yoshida, Munenori

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en Yoshida, Munenori

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Ogura, Yuichiro

× Ogura, Yuichiro

en Ogura, Yuichiro

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抄録(英)
内容記述タイプ Other
内容記述 Purpose: To study the structural and functional changes of retinal ischemia and investigate their association with macular edema (ME) or microaneurysm (MA) formation in eyes with retinal vein occlusion (RVO). Methods: Sixty eyes of 30 patients (27 eyes with branch [b]RVO, 3 with central RVO, and 30 fellow eyes) were retrospectively reviewed. Optical coherence tomography (OCT), OCT angiography (OCTA), and microperimetry were performed simultaneously to measure retinal thickness and sensitivity. The presence of ME or MA was also assessed using OCT and fluorescein angiography. Results: The mean retinal sensitivity in the nonperfused areas (NPAs) deteriorated, and this was significantly (r = –0.379, p = 0.0391*) and inversely correlated with duration from disease onset. ME and MA were unlikely to be observed around the area where the retinal sensitivity decreased. In the NPAs, the mean retinal thickness of the superficial capillary plexus (SCP) (p < 0.0001), deep capillary plexus (DCP) (p = 0.0323), and outer retina (p = 0.0008) were significantly thinner than those in the fellow eyes, respectively. Multivariate regression analysis revealed that the thicknesses of the DCP (β: 0.3107, p = 0.0007) and outer retina (β: 0.3482, p = 0.0001) were the independent correlative factors of the retinal sensitivity, but that SCP thickness was not. Conclusion: Deep retinal thinning in NPAs was correlated significantly with a decreased retinal sensitivity, which might be a negative predictor of ME and MA in eyes with RVO.
書誌情報 en : Ophthalmic Research

巻 61, 号 4, p. 218-225, 発行日 2019-04
出版者
出版者 Karger
ISSN
収録物識別子タイプ ISSN
収録物識別子 0030-3747
PubMed番号
関連タイプ isVersionOf
識別子タイプ PMID
関連識別子 30359965
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1159/000493489
権利
権利情報 © 2018 S. Karger AG, Basel. This is the accepted manuscript version of the article. The formal published version is available at: https://doi.org/10.1159/000493489
著者版フラグ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
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